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DeCS
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Descriptor English:
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Central Nervous System Agents
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Descriptor Spanish:
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fármacos del sistema nervioso central
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Descriptor Portuguese:
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Fármacos do Sistema Nervoso Central
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Synonyms English:
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Central Nervous System Drugs
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Tree Number:
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D27.505.954.427
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Definition English:
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A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) |
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Indexing Annotation English:
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GEN or unspecified; prefer specific groups or specific drugs; consider also CENTRAL NERVOUS SYSTEM /drug eff & BRAIN /drug eff; DF: CNS AGENTS
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History Note English:
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79; was NON MESH before 1979
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Allowable Qualifiers English:
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Record Number:
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2526
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Unique Identifier:
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D002491
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Occurrence in VHL:
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Similar:
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DeCS
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